[ImTouchk]

Code:

public OnPlayerPickUpPickup(playerid, pickupid) 
{ 
    if(pickupid == gift1) 
    { 
        if(gift1 == 0) 
        { 
        gift1=1; 
        SendClientMessage(playerid,0x912334,"got it"); 
        } 
        else if(gift1 == 1) 
        { 
        SendClientMessage(playerid,0x912334,"Lool"); 
        } 
    } 
    return 1; 
}

first, you have to move it from static to dynamic. whether you need to use streamer plugin, who can be found on the internet.
Now, let's start:

Code:

    gift1 = CreatePickup(19055, 2, 1976.1938,-2380.4646,13.5469, -1);

Code:

gift1 = CreateDynamicPickup(19055, 2, 1976.1938,-2380.4646,13.5469, -1);

Code:

public OnPlayerPickUpPickup(playerid, pickupid) 
{ 
    if(pickupid == gift1) 
    { 
        if(gift1 == 0) 
        { 
        gift1=1; 
        SendClientMessage(playerid,0x912334,"got it"); 
        } 
        else if(gift1 == 1) 
        { 
        SendClientMessage(playerid,0x912334,"Lool"); 
        } 
    } 
    return 1; 
}

Code:

public OnPlayerPickUpDynamicPickup(playerid, pickupid) 
{ 
    if(pickupid == gift1) 
    { 
        if(gift1 == 0) 
        { 
        gift1=1; 
        SendClientMessage(playerid,0x912334,"got it"); 
        } 
        else if(gift1 == 1) 
        { 
        SendClientMessage(playerid,0x912334,"Lool"); 
        } 
    } 
    return 1; 
}

now, what do you want to mean from 'if(gift1 == 0)' ?
make a variable in enum pInfo(or how do you have) with name pGiftTaken for example

Code:

enum pInfo {
pGiftTaken
}

the step two, go on OnPlayerPickUpDynamicPickup:

Code:

public OnPlayerPickUpPickup(playerid, pickupid) 
{ 
    if(pickupid == gift1) 
    { 
        if(PlayerInfo[playerid][pGiftTaken] == 0) 
        { 
                PlayerInfo[playerid][pGiftTaken] = 1;
                SendClientMessage(playerid,0x912334,"got it"); 
        } 
        else if(PlayerInfo[playerid][pGiftTaken] == 1) 
        { 
               SendClientMessage(playerid,0x912334,"Lool");
        } 
    } 
    return 1; 
}

and now you can make this variable saveable(mysql or what you want)
this may fix your problem