[p0o]

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Tried re-installing San Andreas? Restarting your computer? Installing the latest version of SA-MP ? Got the latest video drivers? Got the latest DirectX? troubleshooting ftw

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goto My Documents/GTA San Andreas User Files/ and copy paste gta_sa.set into your desktop or somewhere then delete it from the folder try again if it works replace it with the one on your desktop and your fine.

Make sure, you did all those things..
If this doesn't work, your problem is elsewhere, try un-installing San Andreas and then making sure all the San Andreas program files are deleted from your computer, then re-install the San Andreas game. Your best bet is to have a version that isn't downloaded but bought legally. I have 75% sure that you downloaded it.